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Cell2Sentence (C2S) is an open-source framework from the van Dijk Lab that represents single-cell RNA-seq profiles as textual “cell sentences” (genes ordered by expression), enabling large language models to natively model biology. The project includes code, docs, and open models (C2S-Scale) released with Google Research/DeepMind for state-of-the-art single-cell tasks like cell typing, perturbation prediction, and virtual cell generation.

Cell2Sentence

cell2sentence

Open-source framework that turns single-cell gene expression into 'cell sentences' so LLMs can analyze and generate biology insights.

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Cell2Sentence