# AI Agent Developments: March 21, 2025 NVIDIA’s GTC 2025 dominated headlines with major AI agent advancements, unveiling the Blackwell Ultra AI Factory Platform designed for industrial-scale reasoning and agentic AI workloads. The platform integrates open-source Llama Nemotron models optimized for building collaborative AI agents, while CEO Jensen Huang emphasized that agentic AI now requires 100x more computing power than anticipated in 2024. Trend Micro open-sourced Trend Cybertron, a specialized cybersecurity AI agent framework fine-tuned on NVIDIA’s infrastructure. The tool aims to automate threat detection and risk assessment using real-time data from 250M+ global sensors. Meanwhile, ConcertAI and NVIDIA announced a partnership to deploy hierarchical AI agents for oncology trials, including specialized agents for molecular diagnostics and trial design oversight. Despite progress, skepticism persists. A CB Insights survey of 40+ enterprises revealed reliability gaps and security risks in AI agents, with some calling Manus—a viral Chinese agent—overhyped due to inconsistent outputs. OpenAI expanded its enterprise toolkit with a Responses API and Agents SDK, enabling developers to build multi-agent workflows with built-in search and monitoring tools. Microsoft’s Phi-3 small language models saw 4.5M Hugging Face downloads, showcasing demand for efficient, open-source reasoning AI. In humanitarian tech, Mercy Corps deployed AI agents to streamline crisis response across 40 countries, reducing aid delivery times with predictive analytics. Today’s developments highlight AI agents’ growing role in healthcare, cybersecurity, and infrastructure, though challenges around transparency and scalability remain central to adoption.